USC-OGP 2-DE database Two-dimensional polyacrylamide gel electrophoresis database

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Searching in 'USC-OGP 2-DE database' for entry matching: H33_HUMAN USC-OGP 2-DE database:  H33_HUMAN H33_HUMAN General information about the entry View entry in simple text format Entry name H33_HUMAN Primary accession number P84243 Secondary accession number(s) P06351 integrated into USC-OGP 2-DE database on  January 17, 2017 (release 1) 2D Annotations were last modified on January 17, 2017 (version 1) General Annotations were last modified on  April 5, 2017 (version 2) Name and origin of the protein Description RecName: Full=Histone H3.3;. Gene name Name=H3F3A Synonyms=H3.3A, H3F3 ORFNames=PP781    and Name=H3F3B Synonyms=H3.3B Annotated species Homo sapiens (Human) [TaxID: 9606] Taxonomy Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia; Eutheria; Euarchontoglires; Primates; Haplorrhini; Catarrhini; Hominidae; Homo. References [1]   2D GEL CHARACTERIZATION Author 1., Author 2. Submitted (Mar-2011) to Current 2D PAGE maps for identified proteins How to interpret a protein UVEAL_MELANOMA_3-10 {UVEAL MELANOMA 3-10} Homo sapiens (Human)   map experimental info   UVEAL_MELANOMA_3-10 MAP LOCATIONS: SPOT OGP-1359: pI=5.15; Mw=12450 Cross-references UniProtKB/Swiss-Prot P84243; H33_HUMAN. 2D PAGE maps for identified proteins How to interpret a protein map You may obtain an estimated location of the protein on various 2D PAGE maps, provided the whole amino acid sequence is known. The estimation is obtained according to the computed protein's pI and Mw. Warning 1: the displayed region reflects an area around the theoretical pI and molecular weight of the protein and is only provided for the user's information. It should be used with caution, as the experimental and theoretical positions of a protein may differ significantly. Warning 2: the 2D PAGE map is built on demand. This may take some few seconds to be computed. External data extracted from UniProtKB/Swiss-Prot Extracted from UniProtKB/Swiss-Prot, release: 0.0 Entry name H33_HUMAN Primary accession number P84243 Secondary accession number(s) P06351 P33155 Q5VV55 Q5VV56 Q66I33 Q9V3W4 Sequence was last modified on  January 23, 2007 (version 2) Annotations were last modified on  March 15, 2017 (version 143) Name and origin of the protein Description RecName: Full=Histone H3.3; Gene name Name=H3F3A Synonyms=H3.3A, H3F3 ORFNames=PP781    and Name=H3F3B Synonyms=H3.3B Encoded on Name=H3F3A; Synonyms=H3.3A, H3F3; ORFNames=PP781; and Name=H3F3B; Synonyms=H3.3B Keywords 3D-structure; Acetylation; Chromosome; Citrullination; Complete proteome; Direct protein sequencing; DNA-binding; Methylation; Nucleosome core; Nucleus; Phosphoprotein; Reference proteome; Ubl conjugation. Copyright Copyrighted by the UniProt Consortium, see http://www.uniprot.org/help/license. Distributed under the Creative Commons Attribution-NoDerivs License Cross-references EMBL M11354; AAA52653.1; -; mRNA EMBL M11353; AAA52654.1; -; mRNA EMBL Z48950; CAA88778.1; -; Genomic_DNA EMBL X05855; CAA29288.1; ALT_SEQ; Genomic_DNA EMBL X05856; CAA29288.1; JOINED; Genomic_DNA EMBL X05857; CAA29288.1; JOINED; Genomic_DNA EMBL AF218029; AAG17271.1; -; mRNA EMBL BX537379; CAD97621.1; -; mRNA EMBL AL512343; CAH73371.1; ALT_SEQ; Genomic_DNA EMBL AL512343; CAH73372.1; -; Genomic_DNA EMBL BC001124; AAH01124.1; -; mRNA EMBL BC006497; AAH06497.1; -; mRNA EMBL BC012813; AAH12813.1; -; mRNA EMBL BC017558; AAH17558.1; -; mRNA EMBL BC029405; AAH29405.1; -; mRNA EMBL BC038989; AAH38989.1; -; mRNA EMBL BC066901; -; NOT_ANNOTATED_CDS; mRNA EMBL BC067757; -; NOT_ANNOTATED_CDS; mRNA EMBL BC081560; AAH81560.1; -; mRNA EMBL BC081561; AAH81561.1; -; mRNA EMBL BC095447; AAH95447.1; -; mRNA EMBL BC108701; AAI08702.1; -; mRNA CCDS CCDS11729.1; -; . CCDS CCDS1550.1; -; . PIR A27501; HSHU33; . RefSeq NP_002098.1; NM_002107.4; . RefSeq NP_005315.1; NM_005324.4; . UniGene Hs.180877; -; . UniGene Hs.533624; -; . UniGene Hs.726012; -; . PDB 2L43; NMR; -; A=2-13 PDB 3ASK; X-ray; 2.90 A; P/Q/R=2-14 PDB 3ASL; X-ray; 1.41 A; B=2-12 PDB 3AV2; X-ray; 2.80 A; A/E=1-136 PDB 3JVK; X-ray; 1.80 A; C=13-20 PDB 3MUK; X-ray; 1.75 A; D=22-29 PDB 3MUL; X-ray; 1.65 A; D=13-20 PDB 3QL9; X-ray; 0.93 A; C=2-16 PDB 3QLA; X-ray; 1.60 A; C/F=2-16 PDB 3QLC; X-ray; 2.50 A; C/D=2-16 PDB 3WTP; X-ray; 2.67 A; E=1-136 PDB 4GNE; X-ray; 1.47 A; B=2-8 PDB 4GNF; X-ray; 1.55 A; C=2-16 PDB 4GNG; X-ray; 1.73 A; B/F=2-16 PDB 4GU0; X-ray; 3.10 A; E/F=2-27 PDB 4GUR; X-ray; 2.51 A; C=2-22 PDB 4GUS; X-ray; 2.23 A; C=2-22 PDB 4GY5; X-ray; 2.96 A; E/F=2-18 PDB 4H9N; X-ray; 1.95 A; A=2-136 PDB 4H9O; X-ray; 2.05 A; A=2-136 PDB 4H9P; X-ray; 2.20 A; A=2-136 PDB 4H9Q; X-ray; 1.95 A; A=2-136 PDB 4H9R; X-ray; 2.20 A; A=2-136 PDB 4H9S; X-ray; 2.60 A; A/B=2-136 PDB 4HGA; X-ray; 2.80 A; B=1-136 PDB 4L58; X-ray; 1.48 A; B=2-13 PDB 4N4I; X-ray; 2.00 A; B=20-43 PDB 4O62; X-ray; 1.78 A; D=2-12 PDB 4QQ4; X-ray; 1.75 A; C/D=2-16 PDB 4TMP; X-ray; 2.30 A; B/D=2-12 PDB 4U7T; X-ray; 2.90 A; F/G=2-13 PDB 4W5A; X-ray; 2.60 A; C/D/F=2-16 PDB 5AY8; X-ray; 2.80 A; A/E=1-134 PDB 5B32; X-ray; 2.35 A; A/E=1-136 PDB 5B33; X-ray; 2.92 A; A/E=1-136 PDB 5BNV; X-ray; 2.79 A; A/D=58-136 PDB 5BNX; X-ray; 2.31 A; A=58-136 PDB 5DWQ; X-ray; 2.36 A; F/G=14-31 PDB 5DX0; X-ray; 2.05 A; F/G/H/I=14-31 PDB 5JA4; X-ray; 2.42 A; A=58-136 PDB 5JJY; X-ray; 2.05 A; B=30-43 PDB 5JLB; X-ray; 1.50 A; B=30-43 PDB 5KDM; X-ray; 3.50 A; A=2-136 PDBsum 2L43; -; . PDBsum 3ASK; -; . PDBsum 3ASL; -; . PDBsum 3AV2; -; . PDBsum 3JVK; -; . PDBsum 3MUK; -; . PDBsum 3MUL; -; . PDBsum 3QL9; -; . PDBsum 3QLA; -; . PDBsum 3QLC; -; . PDBsum 3WTP; -; . PDBsum 4GNE; -; . PDBsum 4GNF; -; . PDBsum 4GNG; -; . PDBsum 4GU0; -; . PDBsum 4GUR; -; . PDBsum 4GUS; -; . PDBsum 4GY5; -; . PDBsum 4H9N; -; . PDBsum 4H9O; -; . PDBsum 4H9P; -; . PDBsum 4H9Q; -; . PDBsum 4H9R; -; . PDBsum 4H9S; -; . PDBsum 4HGA; -; . PDBsum 4L58; -; . PDBsum 4N4I; -; . PDBsum 4O62; -; . PDBsum 4QQ4; -; . PDBsum 4TMP; -; . PDBsum 4U7T; -; . PDBsum 4W5A; -; . PDBsum 5AY8; -; . PDBsum 5B32; -; . PDBsum 5B33; -; . PDBsum 5BNV; -; . PDBsum 5BNX; -; . PDBsum 5DWQ; -; . PDBsum 5DX0; -; . PDBsum 5JA4; -; . PDBsum 5JJY; -; . PDBsum 5JLB; -; . PDBsum 5KDM; -; . ProteinModelPortal P84243; -; . SMR P84243; -; . BioGrid 109272; 108; . BioGrid 109273; 17; . DIP DIP-40046N; -; . IntAct P84243; 41; . MINT MINT-4825076; -; . STRING 9606.ENSP00000355778; -; . iPTMnet P84243; -; . PhosphoSitePlus P84243; -; . SwissPalm P84243; -; . BioMuta H3F3A; -; . DMDM 55977062; -; . EPD P84243; -; . MaxQB P84243; -; . PaxDb P84243; -; . PeptideAtlas P84243; -; . PRIDE P84243; -; . TopDownProteomics P84243; -; . DNASU 3020; -; . DNASU 3021; -; . Ensembl ENST00000254810; ENSP00000254810; ENSG00000132475; . Ensembl ENST00000366813; ENSP00000355778; ENSG00000163041; . Ensembl ENST00000366815; ENSP00000355780; ENSG00000163041; . Ensembl ENST00000366816; ENSP00000355781; ENSG00000163041; . Ensembl ENST00000586607; ENSP00000466020; ENSG00000132475; . Ensembl ENST00000587560; ENSP00000468714; ENSG00000132475; . Ensembl ENST00000589599; ENSP00000465813; ENSG00000132475; . GeneID 3020; -; . GeneID 3021; -; . KEGG hsa:3020; -; . KEGG hsa:3021; -; . UCSC uc001hpw.4; human; . CTD 3020; -; . CTD 3021; -; . DisGeNET 3020; -; . DisGeNET 3021; -; . GeneCards H3F3A; -; . GeneCards H3F3B; -; . GeneCards MIR4738; -; . H-InvDB HIX0135637; -; . HGNC HGNC:4764; H3F3A; . HGNC HGNC:4765; H3F3B; . HPA CAB011481; -; . HPA CAB037166; -; . HPA CAB037178; -; . HPA CAB037187; -; . HPA CAB037221; -; . HPA HPA042570; -; . MIM 601058; gene; . MIM 601128; gene; . neXtProt NX_P84243; -; . OpenTargets ENSG00000132475; -; . OpenTargets ENSG00000163041; -; . PharmGKB PA29140; -; . eggNOG KOG1745; Eukaryota; . eggNOG COG2036; LUCA; . GeneTree ENSGT00760000118967; -; . HOVERGEN HBG001172; -; . InParanoid P84243; -; . KO K11253; -; . OMA CHASMAR; -; . OrthoDB EOG091G0XGD; -; . PhylomeDB P84243; -; . TreeFam TF314241; -; . Reactome R-HSA-201722; Formation of the beta-catenin:TCF transactivating complex; . Reactome R-HSA-212300; PRC2 methylates histones and DNA; . Reactome R-HSA-2299718; Condensation of Prophase Chromosomes; . Reactome R-HSA-2559580; Oxidative Stress Induced Senescence; . Reactome R-HSA-2559582; Senescence-Associated Secretory Phenotype (SASP); . Reactome R-HSA-427359; SIRT1 negatively regulates rRNA Expression; . Reactome R-HSA-427389; ERCC6 (CSB) and EHMT2 (G9a) positively regulate rRNA expression; . Reactome R-HSA-427413; NoRC negatively regulates rRNA expression; . Reactome R-HSA-5250924; B-WICH complex positively regulates rRNA expression; . Reactome R-HSA-5334118; DNA methylation; . Reactome R-HSA-5578749; Transcriptional regulation by small RNAs; . Reactome R-HSA-5617472; Activation of anterior HOX genes in hindbrain development during early embryogenesis; . Reactome R-HSA-5625886; Activated PKN1 stimulates transcription of AR (androgen receptor) regulated genes KLK2 and KLK3; . Reactome R-HSA-73728; RNA Polymerase I Promoter Opening; . Reactome R-HSA-73777; RNA Polymerase I Chain Elongation; . Reactome R-HSA-912446; Meiotic recombination; . Reactome R-HSA-977225; Amyloid fiber formation; . Reactome R-HSA-983231; Factors involved in megakaryocyte development and platelet production; . SIGNOR P84243; -; . ChiTaRS H3F3B; human; . EvolutionaryTrace P84243; -; . GeneWiki H3F3A; -; . PRO PR:P84243; -; . Proteomes UP000005640; Chromosome 1; . Proteomes UP000005640; Chromosome 17; . Bgee ENSG00000132475; -; . CleanEx HS_H3F3A; -; . CleanEx HS_H3F3B; -; . ExpressionAtlas P84243; baseline and differential; . Genevisible P84243; HS; . GO GO:0001740; C:Barr body; IEA:Ensembl; . GO GO:0070062; C:extracellular exosome; IDA:UniProtKB; . GO GO:0005576; C:extracellular region; TAS:Reactome; . GO GO:0000228; C:nuclear chromosome; IDA:UniProtKB; . GO GO:0000784; C:nuclear chromosome; telomeric region; IDA:BHF-UCL GO GO:0000788; C:nuclear nucleosome; IDA:UniProtKB; . GO GO:0005654; C:nucleoplasm; TAS:Reactome; . GO GO:0000786; C:nucleosome; IDA:UniProtKB; . GO GO:0005634; C:nucleus; IDA:UniProtKB; . GO GO:0043234; C:protein complex; IDA:UniProtKB; . GO GO:0042393; F:histone binding; IPI:UniProtKB; . GO GO:0031492; F:nucleosomal DNA binding; IDA:UniProtKB; . GO GO:0000979; F:RNA polymerase II core promoter sequence-specific DNA binding; IDA:UniProtKB; . GO GO:0000980; F:RNA polymerase II distal enhancer sequence-specific DNA binding; IDA:UniProtKB; . GO GO:0007596; P:blood coagulation; TAS:Reactome; . GO GO:0008283; P:cell proliferation; IEA:Ensembl; . GO GO:0044267; P:cellular protein metabolic process; TAS:Reactome; . GO GO:0000183; P:chromatin silencing at rDNA; TAS:Reactome; . GO GO:0006336; P:DNA replication-independent nucleosome assembly; IDA:UniProtKB; . GO GO:0007566; P:embryo implantation; IEA:Ensembl; . GO GO:0031047; P:gene silencing by RNA; TAS:Reactome; . GO GO:0008584; P:male gonad development; IEA:Ensembl; . GO GO:0035264; P:multicellular organism growth; IEA:Ensembl; . GO GO:0042692; P:muscle cell differentiation; IEA:Ensembl; . GO GO:1902340; P:negative regulation of chromosome condensation; IEA:Ensembl; . GO GO:0045814; P:negative regulation of gene expression; epigenetic; TAS:Reactome GO GO:0006334; P:nucleosome assembly; IDA:UniProtKB; . GO GO:0006997; P:nucleus organization; IEA:Ensembl; . GO GO:0048477; P:oogenesis; IEA:Ensembl; . GO GO:0001649; P:osteoblast differentiation; IEA:Ensembl; . GO GO:0031508; P:pericentric heterochromatin assembly; IEA:Ensembl; . GO GO:0030307; P:positive regulation of cell growth; IMP:UniProtKB; . GO GO:0045815; P:positive regulation of gene expression; epigenetic; TAS:Reactome GO GO:0090230; P:regulation of centromere complex assembly; IEA:Ensembl; . GO GO:0007338; P:single fertilization; IEA:Ensembl; . GO GO:0007286; P:spermatid development; IEA:Ensembl; . GO GO:0032200; P:telomere organization; TAS:BHF-UCL; . GO GO:0031509; P:telomeric heterochromatin assembly; IEA:Ensembl; . Gene3D 1.10.20.10; -; 1; . InterPro IPR009072; Histone-fold; . InterPro IPR007125; Histone_H2A/H2B/H3; . InterPro IPR000164; Histone_H3/CENP-A; . PANTHER PTHR11426; PTHR11426; 1; . Pfam PF00125; Histone; 1; . PRINTS PR00622; HISTONEH3; . SMART SM00428; H3; 1; . SUPFAM SSF47113; SSF47113; 1; . PROSITE PS00322; HISTONE_H3_1; 1; . PROSITE PS00959; HISTONE_H3_2; 1; .

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